Seth MacFarlane, the creator of the primetime fixture Family Guy, has said if he had his own way, he would take the series to another network just to escape Fox News and Tucker Carlson.

"Tucker Carlson's latest opinion piece once again makes me wish Family Guy was on any other network. Look, Fox, we both know this marriage isn't working anymore. The sex is only once a year, I don't get along with your mother, and well... I've been having an affair with NBC," MacFarlane tweeted over the weekend.

In 2020, MacFarlane signed a "mega TV overall deal" with NBC Universal Content Studios, signaling the end of his long-time (and very profitable) relationship with 20th Century Fox Television.

While it is unclear which opinion piece of Carlson's he is referring to, however, Carlson is notorious for his right-wing rants and outspoken personality against the status quo. The TV news host claimed that the Democrats and the CDC "have been lying about COVID and the vaccine," and that the chief medical adviser to Joe Biden and part of Donald Trump's former White House Coronavirus Task Force, Dr. Fauci "created COVID."

Family Guy has been a popular fixture on television since 1999, however, despite being on the same network, MacFarlane and the team have made their opinions of Fox News very apparent on the show... and this tweet could signal the end of his relationship with Fox.

The creator of the long-running animated sitcom tweeted in 2018 that he was "embarrassed" to work for Fox after Carlson told Fox News faithful watchers to ignore other outlets.

Tucker Carlson was recently confronted by a man in Montana who called the Fox News host "the worst human being known to mankind."

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The video, which quickly circulated the internet, shows Dan Bailey talking closely to Carlson inside a Montana fly fishing shop. Carlson can be heard in the video saying, "I appreciate that" and "I'm not going to debate," according to The Independent.

Tucker Carlson currently has the highest-viewed show on the network. Whether Macfarlane was just blowing off some steam with the Tweet or actively maneuvering to move Family Guy to another network is unclear, however, last September Fox announced that the show was renewed for 2 more seasons.